The function estimates the compartment proportions from an estimated signature matrix using unmix

estimateUnmix(yref, sigs, shift.range = 10^(1:10), logTransform = F)

Arguments

yref

matrix, numeric expression matrix

sigs

matrix, numeric expression compartment-specific sig matrix

shift.range

vector, numeric vector for gene expression shifts

logTransform

logical, T/F to logTransform data, defaults to F

Value

list with cell-type proportions and expression profiles